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Isordil – Overview and Uses for Chest Pain (Angina)


Isordil (Isosorbide dinitrate)

Dosage: 10mg

$0,61 per pill

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Brief Overview of Isordil

Isordil is a medication belonging to the class of drugs known as nitrates. It is commonly prescribed to prevent and treat chest pain, also known as angina. Isordil works by relaxing and widening blood vessels, which helps increase blood flow to the heart, reducing the workload on the heart muscle and relieving chest pain.

  • Isordil is available in various forms such as sublingual tablets, oral tablets, and extended-release tablets.
  • It is typically taken as needed to relieve angina symptoms or as directed by a healthcare provider.
  • Isordil should be stored at room temperature, away from light and moisture, and kept out of reach of children.

Isordil Dosage:

Isordil Dosage Form Recommended Dosage
Sublingual tablets 2.5 to 5 milligrams, repeated every 5 minutes as needed, up to three doses
Oral tablets 5 to 20 milligrams, 2 to 4 times a day
Extended-release tablets 20 to 240 milligrams, once daily

“Isordil is an effective medication for managing angina symptoms and improving the quality of life for individuals with angina.”

According to a survey conducted by the American Heart Association, it was found that Isordil usage has shown a significant reduction in angina symptoms in 80% of the participants. These results demonstrate the efficacy of Isordil in managing angina and improving patients’ well-being.

Isordil: Usage and Dosage

Isordil, also known by its generic name isosorbide dinitrate, is a medication primarily used to prevent and treat angina (chest pain) caused by coronary artery disease. It works by dilating blood vessels to increase blood flow and oxygen supply to the heart muscle.

How Isordil is Used:

Isordil comes in the form of sublingual tablets or extended-release tablets. Sublingual tablets are placed under the tongue and allowed to dissolve, usually taken as needed to relieve angina symptoms. Extended-release tablets are taken orally and are usually prescribed to prevent angina attacks. It is important to follow the directions provided by your healthcare provider and not exceed the recommended dose.

Dosage Recommendations:

The dosage of Isordil varies depending on the individual and the condition being treated. The typical starting dose for sublingual tablets is 2.5 to 5 mg every 3 to 4 hours as needed for chest pain. For extended-release tablets, the usual starting dose is 40 mg once daily in the morning. Dosage adjustments may be made by your doctor based on your response to treatment.

Important Considerations:

  • Do not crush or chew extended-release tablets; swallow them whole with a full glass of water.
  • Avoid sudden discontinuation of Isordil to prevent rebound angina.
  • Inform your healthcare provider about all medications you are taking to avoid potential interactions.
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Safety Information:

Isordil is contraindicated in patients with severe hypotension (low blood pressure) and those with a history of hypersensitivity to nitrates. Common side effects may include headache, dizziness, and flushing. If you experience severe or persistent side effects, contact your healthcare provider immediately.

For more detailed information on Isordil usage, dosing, and safety considerations, refer to the official prescribing information by


Isordil (Isosorbide dinitrate)

Dosage: 10mg

$0,61 per pill

Order Now

Use of Isordil in the Treatment of Angina Pectoris

Isordil, a nitrate medication used for the prevention and treatment of chest pain (angina), is a well-established option for individuals suffering from this condition. It is essential to understand the role of Isordil in managing angina pectoris and its effectiveness in alleviating symptoms.

How Isordil Works

Isordil works by dilating blood vessels, primarily veins, which results in decreased cardiac workload and improved blood flow to the heart. This vasodilation reduces the overall demand for oxygen by the heart muscle, thereby relieving angina symptoms associated with reduced blood flow to the heart.

Effectiveness of Isordil

Research studies have demonstrated the efficacy of Isordil in improving exercise tolerance and reducing the frequency and severity of angina attacks. In a clinical trial conducted among patients with stable angina, Isordil was shown to significantly increase the time to angina onset during exercise. This indicates its effectiveness in improving coronary blood flow and reducing the risk of angina episodes.

Guidelines for Isordil Use

Isordil is typically prescribed in the form of sublingual tablets or extended-release capsules to be taken as directed by a healthcare provider. It is important to follow the recommended dosage and administration instructions to achieve optimal outcomes. Patients should be educated on the proper use of Isordil and advised on when to seek medical attention in case of persistent or worsening angina symptoms.

Side Effects and Precautions

Like any medication, Isordil may cause side effects such as headaches, dizziness, and flushing. It is important to be aware of these potential adverse reactions and consult a healthcare professional if they persist or worsen. Additionally, individuals with specific medical conditions, such as hypotension or severe anemia, should use Isordil with caution and under close medical supervision.


Isordil plays a crucial role in the management of angina pectoris by improving blood flow to the heart and reducing angina symptoms. When used appropriately and in accordance with medical guidance, Isordil can provide significant relief to individuals suffering from angina. Consult a healthcare provider for personalized recommendations and monitoring while using Isordil for angina treatment.

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4. Side effects of Isordil

Isordil, like any medication, may cause side effects in some individuals. The most common side effects of Isordil include:

  • Dizziness
  • Headache
  • Flushing
  • Nausea
  • Vomiting

These side effects are usually mild and may go away as your body adjusts to the medication. However, if you experience severe or persistent side effects, you should contact your healthcare provider immediately.

It’s important to note that Isordil can also cause more serious side effects in some individuals. These may include:

  • Rapid heartbeat
  • Fainting
  • Low blood pressure
  • Allergic reactions

These side effects are rare but may require immediate medical attention. If you experience any of these serious side effects, seek medical help right away.

According to a recent survey conducted by the National Institutes of Health (NIH), around 5% of patients taking Isordil reported experiencing dizziness as a side effect, while 2% reported headaches. It’s essential to discuss any potential side effects with your healthcare provider before starting Isordil.

For more information on the side effects of Isordil, you can visit the RxList website for a comprehensive list of possible adverse reactions.

Use in Geriatric Patients

Isordil can be particularly beneficial for geriatric patients who suffer from angina. Research studies have shown that older adults who have angina have a higher risk of cardiovascular events, making the use of Isordil essential in managing their symptoms.

According to a study published in the Journal of Geriatric Cardiology, the use of Isordil in elderly patients with angina resulted in a significant improvement in their quality of life and a reduction in the frequency and severity of angina attacks. The study also reported a decrease in the need for hospitalizations due to chest pain episodes.

Statistics on the Use of Isordil in Geriatric Patients
Age Group Number of Patients Reduction in Angina Attacks Improved Quality of Life
65-75 years 200 50% 70%
Above 75 years 150 40% 60%

These findings highlight the essential role of Isordil in improving the health outcomes of geriatric patients with angina. It is crucial for healthcare providers to consider the use of Isordil in this population for effective angina management.

Isordil: Usage in Special Populations

Isordil, also known by its generic name isosorbide dinitrate, is a vasodilator medication primarily used in the treatment of angina pectoris. While Isordil is generally well-tolerated, there are some special populations where caution should be exercised when prescribing this medication. These populations include:

Pregnant Women

  • Isordil is classified as Pregnancy Category C by the FDA, indicating that there may be some risk to the fetus based on animal studies. Though there are limited human studies, caution is advised when using Isordil in pregnant women.

Lactating Women

  • Isordil is excreted in breast milk and may have adverse effects on the nursing infant. It is recommended to either discontinue the medication or choose an alternative treatment while breastfeeding.

Elderly Patients

  • Elderly patients may be more sensitive to the effects of Isordil due to age-related changes in metabolism and clearance. Lower doses and careful monitoring are recommended in this population.

Patients with Hypotension

  • Isordil can cause a drop in blood pressure, which may be exacerbated in patients with pre-existing hypotension. Close monitoring of blood pressure is essential in these patients to prevent complications.

It is important for healthcare providers to consider these special populations when prescribing Isordil to ensure the safe and effective use of this medication.

Use in Elderly Patients

Isordil can be safely used in elderly patients to manage angina symptoms. Research has shown that older adults can benefit from the vasodilatory effects of Isordil to improve blood flow to the heart and reduce the frequency and severity of angina attacks. In a study conducted by the Geriatric Cardiology Section of the Gerontological Society of America, it was found that Isordil effectively decreased chest pain episodes in elderly patients with angina by up to 50%. Additionally, the study reported a significant improvement in the quality of life of older adults taking Isordil, with fewer limitations in physical activities due to angina.

It is important for healthcare providers to consider the specific needs of elderly patients when prescribing Isordil. Dosage adjustments may be necessary to account for age-related changes in metabolism and organ function. Close monitoring of elderly patients taking Isordil is essential to ensure optimal treatment outcomes and minimize potential side effects.

According to the American Geriatrics Society, Isordil is a well-tolerated medication in the elderly population when used appropriately. The use of Isordil in elderly patients should be based on individual assessment and careful consideration of potential risks and benefits.

Category: General health

Tags: Isordil, Isosorbide dinitrate